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Topotecan HCl is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM in cell-free assays, respectively.
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Detyrosination of Alpha Tubulin Does Not Stabilize Microtubules In Vivo Daniel R. Webster, Juergen Wehland,* Klaus Weber,* and Gary G. Borisy
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